Despite being warned by the FDA about misleading messages, the pharmaceutical company — now known as Janssen Pharmaceuticals Inc. JPI — continued these tactics.
While it has been observed to be effective in treating a variety of medical conditions, it has been linked to both serious and life-threatening side effects. In September , a lawsuit was settled with a year-old male who developed gynecomastia upon being treated with Risperdal from ages 9 to This abnormal development led to long-term psychological trauma; the settlement amount was undisclosed.
The research, published in Nature , will allow researchers to selectively activate DRD2 thus potentially limiting a host of serious antipsychotic drug side effects such as weight gain, anxiety, dizziness, severe digestive problems, agitation, and many others. About 30 percent of medications on the market activate G-protein coupled receptors on cell surfaces and trigger chemical signals inside cells to yield their therapeutic effects. For antipsychotic medications, one effect is alleviating psychotic symptoms associated with schizophrenia, bipolar disorder and many other psychiatric diseases.
DRD2 has undergone extensive study for 30 years, but until now researchers lacked a high-resolution structure of DRD2 attached to a compound. Risperidone is a commonly prescribed antipsychotic medication which is FDA approved for use for schizophrenia, bipolar disorder, and autism spectrum disorder. Typically scientists have solved the chemical structure of proteins using a technique called X-Ray crystallography. However, getting the DRD2 protein to crystalize with a drug bound to it had been impossible for decades because receptors are notoriously fickle proteins — small, fragile, and typically in motion as they bind to compounds.
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We also discovered through cross-examination that Janssen knew of the relationship well before doctors or families were informed of the risk. Review a brief history of the drug below so you can be informed about your case. Multiple investigations have revealed that producers of Risperdal continued to market the anti-psychotic to children despite knowing that it can cause young boys to develop female breasts. Gynecomastia described the enlargement or swelling of breast tissue in males.
In some instances, Gynecomastia is accompanied by galactorrhea, a condition that triggers a milky white discharge from the nipples. Researchers have linked prolonged usage of Risperdal to an increase in prolactin levels in young boys. This elevated prolactin level is associated with Risperdal-induced gynecomastia. Studies have shown that 3 out of 10 adolescents might develop gynecomastia after taking Risperdal. Our seasoned lawyers keep your case confidential and preserve the client-attorney relationship while assisting you in seeking compensation for your pain and suffering.
With billions of dollars recovered, we have a strong reputation for recovering maximum compensation for our clients. That is the representation you need behind your Risperdal claim. Ready to discuss your case? Reach out to us today to set up a consultation with our caring attorneys.
The drug was only approved to treat schizophrenia in adults. April — A Black Box Warning was added to the drug's label after the FDA learned that the use of the drug among elderly patients with dementia could heighten the possibility of death. June — A study conducted by Duke University revealed that Risperdal could cause male breast growth. The study also showed that the possibility for gynecomastia was stronger with Risperdal than with other antipsychotic medications.
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